The Oncologist Online -- Rubnitz and Pui 2 (6): 374 Table 1

Table 1. Immunologic classification of childhood ALL

Phenotype	Antigen expression	Frequency (%)

Early pre-B	CD19⁺, CD22⁺, CD79a⁺, CD10±, cIgµ^–, sIg ${kappa}$ ^–, sIg ${lambda}$ ^–	55-60
Pre-B	CD19⁺, CD22⁺, CD79a⁺, CD10±, cIgµ⁺, sIgµ^–, sIg ${kappa}$ ^–, sIg ${lambda}$ ^–	20-25
Transitional pre-B	CD19⁺, CD22⁺, CD79a⁺, CD10±, cIgµ⁺, sIgµ⁺, sIg ${kappa}$ ^–, sIg ${lambda}$ ^–	3-5
B cell	CD19⁺, CD22⁺, CD79a⁺, CD10±, cIgµ⁺, sIgµ⁺, sIg ${kappa}$ ⁺, or sIg ${lambda}$ ⁺	2-3
T cell	cCD3⁺ and CD7⁺, plus CD5⁺ or CD2⁺	13-15


Abbreviations: cIg = cytoplasmic immunoglobulin; sIg = surface immunoglobulin; µ = mu heavy-chain protein; ${kappa}$ = kappa light-chain protein; ${lambda}$ = lambda light-chain protein.