Table 1. The Van Nuys Prognostic Index scoring system. One to three points are awarded for each of three different predictors of local breast recurrence (size, margin width, and pathologic classification). Scores for each of the predictors are totaled to yield a VNPI score ranging from a low of 3 to a high of 9. Reprinted with permission [18].

Score 1 2 3 Size (mm) 15 16-40 41 Margins (mm) 10 1-9 < 1 Pathologic classification Non-high grade without necrosis (nuclear grades 1 & 2) Non-high grade with necrosis (nuclear grades 1 & 2) High grade with or without (necrosis (nuclear grade 3)