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Breast Cancer in African-American Women

University of Michigan, Ann Arbor, Michigan, USA

Correspondence: Lisa A. Newman, M.D., M.P.H., F.A.C.S., Associate Professor of Surgery, Director, Breast Care Center, University of Michigan, 1500 East Medical Center Drive, 3308 CGC, Ann Arbor, Michigan 48109, USA. Telephone: 734-936-8771; Fax: 734-647-9647; e-mail: lanewman{at}umich.edu

African-American women face a lower risk of being diagnosed with breast cancer as compared to Caucasian-American women, yet they paradoxically face an increased breast cancer mortality hazard. An increased incidence rate for early-onset disease has also been documented. This manuscript review summarizes the socioeconomic, environmental, genetic, and possible primary tumor biologic factors that may explain these disparities.

Key Words. Breast cancer • African-American women • Outcome disparities

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