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The Oncologist, Vol. 12, No. 5, 512-515, May 2007; doi:10.1634/theoncologist.12-5-512
© 2007 AlphaMed Press

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Breast Cancer

Sentinel Lymph Node Biopsy in Male Patients with Early Breast Cancer

Oreste Gentilinia, Eduardo Chagasa, Stefano Zurridaa,b, Mattia Intraa, Concetta De Ciccoc, Giovanna Gattia, Luzemira Silvaa, Giuseppe Renned, Enrico Cassanoe, Umberto Veronesia,f

aDepartment of Breast Surgery, bUniversity of Milan School of Medicine, cDepartment of Nuclear Medicine, dDepartment of Pathology and Laboratory Medicine, eBreast Imaging Unit, and fScientific Director; European Institute of Oncology, Milan, Italy

Key Words. Male breast cancer • Sentinel lymph node • Surgical treatment

Correspondence: Oreste Gentilini, M.D., Division of Breast Surgery, European Institute of Oncology, Via Ripamonti 435, 20141, Milan, Italy. Telephone: 39-02-57489376; Fax: 39-02-57489780; e-mail: oreste.gentilini{at}ieo.it

Mastectomy with axillary dissection is still the most commonly recommended procedure for male breast cancer. The aim of this study was to retrospectively evaluate our experience in 32 male patients with early breast cancer who underwent sentinel lymph node biopsy (SLNB) and axillary dissection only in cases of metastases in the sentinel lymph node (SLN). The median age was 58 years (range, 33–80). Lymphoscintigraphy was successful in all patients, with a mean number of visualized SLNs per patient of 1.3 (range, 1–2). At surgery, the identification rate of the SLN was 100%, with a mean number of removed SLNs per patient of 1.5 (range, 1–3). Twenty-six patients had negative SLNs, six patients had positive SLNs. Two patients with metastatic SLNs had additional positive nodes. After a median follow-up of 30 months (range, 1–63) no axillary reappearance of the disease occurred. As with women, we recommend SLNB in male patients with breast cancer and clinically negative axilla.

Disclosure of potential conflicts of interest is found at the end of this article.






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