The Oncologist, Vol. 13, No. 9, 1033, September 2008; doi:10.1634/theoncologist.2008-9000
© 2008 AlphaMed Press
In Reply
Claudia I. Henschke
Department of Radiology, New York Presbyterian Hospital, Weill Medical College, New York, New York, USA
Correspondence: Claudia I. Henschke, Ph.D., M.D., Department of Radiology, New York Presbyterian Hospital-Weill Medical College, 525 East 68th Street, New York, New York 10065, USA. Telephone: 212-746-2529; Fax: 212-746-2811; e-mail: chensch{at}med.cornell.edu
Received August 7, 2008;
accepted for publication August 7, 2008.
Disclosure: Dr. Henschke has the following relationships with General Electric and the National Cancer Institute (NCI).
General Electric: Dr. Henschke is a coinventor on a patent and other pending patents owned by Cornell Research Foundation (CRF) which are nonexclusively licensed and related to General Electric for technology involving computer-aided diagnostic methods, including measurement of nodules. She receives royalties from CRF pursuant to Cornell policy, which in turn is consistent with the Bayh-Dole Act.
NCI: Dr. Henschke is compensated for serving as a study section member for NCI.
Dr. Henschke also receives research support in the form of grants and contracts from: American Legacy Foundation, Flight Attendants' Medical Research Institute, NCI, AstraZeneca, Inc., Carestream Health, Inc., and the Foundation for Lung Cancer: early detection, prevention and treatment (primary source of funding was an unrestricted gift by the Vector group, the parent company of Liggett Tobacco).
The following is a listing of the patent and patent applications in which Claudia Henschke is listed as a coinventor.
- U.S. Patent No. 7,274,810 "System and Method for Three-Dimensional Image Rendering and Analysis" (Patent issued to CRF September 25, 2007); CRF has two pending divisional applications related to this patent.
- CRF has two pending patent applications for "System, Method and Apparatus for Small Pulmonary Nodule Computer Aided Diagnosis from Computed Tomography Scans."
- CRF has a pending patent application for "System and Method for Providing Remote Analysis of Medical Data."
- CRF has a pending patent application for "System and Method for Analyzing Medical Data to Determine Diagnosis and Treatment."
- CRF has a pending patent application for "System and Method for Conducting a Clinical Trial Study."
- CRF has a pending PCT application for "Medical Imaging Visibility Index System and Method for Cancer Lesions."
- CRF has a pending patent application (and foreign pending patent applications) for "Method for Expanding the Domain of Imaging Software in a Diagnostic Workup."
- CRF has a pending patent application for "System and Method for Position Matching of a Patient for Medical Imaging."
- Dr. Henschke is an inventor on a pending patent application for "Medical Imaging System for Accurate Measurement Evaluation of Changes in a Target Lesion"(foreign patent applications also pending).
Dr. Bach raised issue about our recent review article in The Oncologist in which we address the concerns that some may have regarding overdiagnosis [1]. I have addressed his particular concern regarding classification of the untreated stage I cases of lung cancer recently [2] and acknowledge the same reclassification issue with the five additional cases of this kind reported in The Oncologist. I agree with Dr. Bach that this is one of many important analytic issues intrinsic to lung cancer screening research.
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REFERENCES
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- Henschke CI, Yankelevitz DF. CT screening for lung cancer: Update 2007. The Oncologist 2008;13:65–78.[Abstract/Free Full Text]
- Henschke C. Clarifying Enrollment Procedures in the Trial of CT Screening for Lung Cancer. N Engl J Med 2008;359:871–873.[Free Full Text]
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